It is possible to lose Christ. Mary and Joseph were able to. Returning from the temple it was customary for the woman to travel with other women and the men to travel with the other men. So mary assumed that He was with Joseph and Joseph assumed He was with Mary.
The most unlikely people can loose Him. Let no missionary, pastor, or sunday school teacher say it can never happen! It can and it does happen, it happened to Mary. No one love Him more than Mary did… she laid Him in a manager and she lingered the longest by the cross.
Your devotion can render you immune from losing Him. Often, the good is the enemy of the best. The most excellent book may help you neglect you bible and tireless christian service may make it possible to exclude secret devotion.
It is possible to forfeit His Presence and not even know it. It is always good to “practice” the presence of the Lord. Talk to Him even when you have nothing in particular it say to Him. There is no greater mistake than to take the Presence of God for granted. Mary and Joseph did and it resulted in many hours of mental anguish He was missing for 4 days.